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Check your work email domain is not being blocked by officewiseco.com at their end i suggest
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Check your work email domain is not being blocked by officewiseco.com at their end i suggest

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You need to determine whether your Exchange server is connecting directly with the recipient system, or if it sends messages to an intermediate system. <br />
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The NSLookup and Telnet tests need to be run from the system that communicates directly with the recipient system.
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You need to determine whether your Exchange server is connecting directly with the recipient system, or if it sends messages to an intermediate system.

The NSLookup and Telnet tests need to be run from the system that communicates directly with the recipient system.

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I have a user trying to send to an email address and we are getting NDRs. &nbsp;The email address appears to be good. &nbsp;We can receive from the email address, but replying or sending a new email to the address doesn't work. &nbsp;<br />
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We are using Outlook 2010 connecting to Exchange 2003. &nbsp;<br />
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We have also tried sending via OWA with no success.<br />
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I was able to successfully send to the email address from my personal hotmail account.<br />
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The NDR is below.<br />
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&nbsp; &nbsp; &nbsp; ddonaldson@officewiseco.co<wbr />m on 4/5/2012 8:36 AM<br />
&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; There was a SMTP communication problem with the recipient's email server. &nbsp;Please contact your system administrator.<br />
&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &lt;smtpa.wbu.edu #5.5.0 smtp;550 #5.1.0 Address rejected ddonaldson@officewiseco.co<wbr />m&gt;
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I have a user trying to send to an email address and we are getting NDRs.  The email address appears to be good.  We can receive from the email address, but replying or sending a new email to the address doesn't work.  

We are using Outlook 2010 connecting to Exchange 2003.  

We have also tried sending via OWA with no success.

I was able to successfully send to the email address from my personal hotmail account.

The NDR is below.

      ddonaldson@officewiseco.com on 4/5/2012 8:36 AM
            There was a SMTP communication problem with the recipient's email server.  Please contact your system administrator.
            <smtpa.wbu.edu #5.5.0 smtp;550 #5.1.0 Address rejected ddonaldson@officewiseco.com>

error sending to an email address

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.

Outlook

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.