I have been having some weird issues tonight, which initially presented itself as an autodiscover issue, and an expired certificate (the certificate in question had actually expired six months ago and had been replaced by a valid certificate). I was finally able to resolve that issue by adding a registry entry to disable loopback. I also removed the expired certificate and re-enabled the current certificate for IMAP, POP, SMTP and IIS. After a reboot I had a conflict between the Default Web Site and SBS Web Applications, but if Default Web Site was stopped, OWA and Autodiscover work. But now I have an even worse problem, one that I can't understand in this series of events - if I try to send an email from outside the domain to any of the users, it bounces back as Unable to Relay. So no outside mail is getting in now and I can't figure out why. Any help would be very much appreciated - this is extremely urgent. Thank you!