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Upgrade Windows 2008 R2 to Enterpise with Exchange 2010

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1. What are the steps to upgrade windows 2008 R2 to enterprise? Are there any issues?

2. Is there an issue upgrading, if Exchange 2010 is installed on the same server?
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Shawn ConstableStaff IT Engineer

Commented:
Im not sure if I understand your question.

Are you attempting to upgrade Windows 2008 R2 Standard to Enterprise?

There is a supported upgrade path:

Upgrade Path

I am not sure I would actually attempt it with Exchange 2010 on it already.
IT Architect
Distinguished Expert 2017
Commented:
It is not recommend or supported to upgrade OS to different version, if exchange is already installed. Better to create new server and move the mailboxes.