OS responds slowly to mouse clicks

My OS (windows 7) is kind of slow and when I use the mouse it usually requires me to click twice to get a response. Yesterday I rebooted my computer and it got much better but then suddenly when I was loading a page through Chrome it started to get slow again. I tried rebooting today but it did not really fix it. It is not the battery in the mouse because I replaced it 2 days ago.
Any solutions would be greatly appreciated.
I am using 3 monitors. It might have gotten worse when I added the third monitor, not sure. Also, I had this problem before when I had the mouse near the speaker and concluded that it was interference from electrical/magnetic waves.
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CallandorConnect With a Mentor Commented:
If it's an RF or Bluetooth mouse, it could be interference from the surroundings that is causing it.  Adding a monitor would definitely fall into this category, so try a wired mouse and see if that clears up the problem.  If it does, you may need to reposition the wireless receiver on your PC so that it has better reception.
jhyieslaConnect With a Mentor Commented:
I would tend to agree that it's not the mouse, but a for sure way to test it would be to temporarily replace it with a wired one.

When things are going slowly, look at Task Manager to see if there are certain processes that are stressing the system, either in CPU usage or RAM usage.  If there are not, then check the System Event log for disk errors; could be that your disk is failing and making everything slow. Next, I'd download memtest86 and test the RAM in the system. Typically if it's bad the test will show large quantities of red lit errors.  Next, I'd download and run the quick scan of malwarebytes to make sure there is no infection going on in the system
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