The office is set up with Server 2008 R2 running on its own hardware, not a VM. 15 MB upload and download Internet connection for only 7 users. We use Office 2010 Pro and have a hosted Exchange 2010 account with a third party provider. Outlook 2010 does not allow access to the Out of Office settings, with a message saying the server is not connected. Email sends and receives fine, calendars are working ok, contacts are up to date. Using direct connection instead of Cached Exchange Mode, and it says we are "Connected" to the server on the status bar. When we log into the hosting control panel via OWA we are able to use the Out of Office settings there, so this is a nuisance more than a panic. Any suggestions?