get-owavirtualdirectory error in exchange 2010


I have 5 exchange 2010 servers setup. No older versions of exchange.
I have problem with opening OWA,ecp,activesync tabs. It takes hours to open and throws attached error for some servers.  even same result with powershell command                       get-owavirtualdirectory .

On internet i found articles talks about co-existance of 2007/2003 but we dont have.
necessary exchange groups are added as administrators to local server by default.

Could you please help to reslove the issue?
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Dmitriy Ilyinsenior system administratorCommented:
first of all i'd like to know that you can resolve all DNS names inside your network that implemented in CAS.
second - did you try to do this
Answer from Gen Lin?
Run ExBPA and see if there any errors..
Are you able to access with out any error?
Check the cert assigned to the OWA website and bindings to make sure all configuration is good.
When did the issue started? Any recent changes made on Exchange servers?
vijaygoturAuthor Commented:
DNS is fine.
All servers are installed with digicert certificate.
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Check the binding of OWA site. Also could you please provide information related to the other questions which I asked?
vijaygoturAuthor Commented:
How should i check binding of web site ? Is removing virtual directory and recreating them will help ?

if yes, what will be ideal process to remove virtual directories in production ?
I'm going through some OWA (or rather IIS more generically) strangeness with Exchange 2010 right now - Mine had to do with MAC clients not getting Autodiscover and EWS properly, but it had to do with my Digicert certificate..  It's a longshot, but since you mentioned it, I thought I'd bring it up...  Even though to me, and everyone else who looked at it, the certificate path looked correct on the servers, it was wrong.  Digicert has a certificate validation program on their website that was able to detect, and correct the situation with the press of a button.  I'd recommend at least trying it..

Having said that, I REALLY expect it's either a DNS issue as stated by your first response, or perhaps a service isn't running, or isn't accessible because of a software firewall.  I'd recommend making sure your firewall is configured to let ANY port talk to ANY port between the Exchange servers and the AD servers...
To Check binding Internet Open IIS Manager > Click on Default Web Site > In the right Action pane You can find Bindings. Check the binding for port 443 (IP and make sure correct cert is assigned.

Did you Run ExBPA on servers to see if there any errors?

Also are you able to access without any error?

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