<div>
Is that server (on which Exchange is installed) a DC?<br />
<br />
If not, or if there are other DC's the server is using, i'D first check the firewall on those. It should allow for everything from exchange server. If you can, disable it at all, even just to test (and disable even the Exchange server's firewall, if u can.).<br />
<br />
Are there DC Orphan records in your domain? Did you demote a DC in the past, when EX was working?<br />
Did it demote successfully?<br />
If not you should look for removing that orphan DC record BEFORE going on with that exchange case. Results in a domain with such problems are unpredictable.<br />
<br />
HTH.
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Is that server (on which Exchange is installed) a DC?

If not, or if there are other DC's the server is using, i'D first check the firewall on those. It should allow for everything from exchange server. If you can, disable it at all, even just to test (and disable even the Exchange server's firewall, if u can.).

Are there DC Orphan records in your domain? Did you demote a DC in the past, when EX was working?
Did it demote successfully?
If not you should look for removing that orphan DC record BEFORE going on with that exchange case. Results in a domain with such problems are unpredictable.

HTH.

<div>
Have a look at the article <br />
<a href="http://support.microsoft.com/kb/271328" rel="ugc nofollow">http://support.microsoft.com/kb/271328</a>
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Have a look at the article
http://support.microsoft.com/kb/271328 [http://support.microsoft.com/kb/271328]

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hi <br />
plz go through attached screenshot. I am getting RPC server unavailable in my exchange server whenever trying to create new user, trying to open any user properties, trying to open exchange tasks.<br />
<a href="https://filedb.experts-exchange.com/incoming/2012/12_w51/623314/rpc-error.JPG" target="_blank" class="file-inline" title="RPC error (19 KB)"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path d="M67.508 468.467c-58.005-58.013-58.016-151.92 0-209.943l225.011-225.04c44.643-44.645 117.279-44.645 161.92 0 44.743 44.749 44.753 117.186 0 161.944l-189.465 189.49c-31.41 31.413-82.518 31.412-113.926.001-31.479-31.482-31.49-82.453 0-113.944L311.51 110.491c4.687-4.687 12.286-4.687 16.972 0l16.967 16.971c4.685 4.686 4.685 12.283 0 16.969L184.983 304.917c-12.724 12.724-12.73 33.328 0 46.058 12.696 12.697 33.356 12.699 46.054-.001l189.465-189.489c25.987-25.989 25.994-68.06.001-94.056-25.931-25.934-68.119-25.932-94.049 0l-225.01 225.039c-39.249 39.252-39.258 102.795-.001 142.057 39.285 39.29 102.885 39.287 142.162-.028A739446.174 739446.174 0 0 1 439.497 238.49c4.686-4.687 12.282-4.684 16.969.004l16.967 16.971c4.685 4.686 4.689 12.279.004 16.965a755654.128 755654.128 0 0 0-195.881 195.996c-58.034 58.092-152.004 58.093-210.048.041z"/></svg>rpc-error.JPG</a>
</div>
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rpc-error.JPG

hi 
plz go through attached screenshot. I am getting RPC server unavailable in my exchange server whenever trying to create new user, trying to open any user properties, trying to open exchange tasks.

RPC Server is Unavailable

Microsoft server applications are those applications developed specifically, but not necessarily exclusively, on the Windows Server platform. In addition to well-known products like SQL Server, Exchange, Internet Information Services (IIS), Microsoft Dynamics, Forefront, Lync and Sharepoint, they include applications like Skype, BizTalk, Hyper-V, Groove and Commerce Server. Server applications are managed with the Microsoft System Center.