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Presumably there actually *is* plenty of disk space! &nbsp;Please check this technet link RTM2007 and see if it applies (opening excel files via IIS):<br />
<a href="http://social.technet.microsoft.com/forums/en-US/officesetupdeployprevious/thread/2c753037-4600-4a4f-abd7-d228e2f20a38/" rel="ugc nofollow">http://social.technet.microsoft.com/forums/en-US/officesetupdeployprevious/thread/2c753037-4600-4a4f-abd7-d228e2f20a38/</a>
</div>


Presumably there actually *is* plenty of disk space!  Please check this technet link RTM2007 and see if it applies (opening excel files via IIS):
http://social.technet.microsoft.com/forums/en-US/officesetupdeployprevious/thread/2c753037-4600-4a4f-abd7-d228e2f20a38/ [http://social.technet.microsoft.com/forums/en-US/officesetupdeployprevious/thread/2c753037-4600-4a4f-abd7-d228e2f20a38/]

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Also try this regsitry fix:<br />
<a href="http://answers.microsoft.com/en-us/office/forum/office_2010-excel/microsoft-excel-cannot-open-or-save-any-more/ab1a73d9-1666-4cf5-a6a7-285d2004dd08" rel="ugc nofollow">http://answers.microsoft.com/en-us/office/forum/office_2010-excel/microsoft-excel-cannot-open-or-save-any-more/ab1a73d9-1666-4cf5-a6a7-285d2004dd08</a><br />
<br />
Suggestion is to:<br />
1.run regedt32<br />
<br />
2.check/change the value of<br />
<br />
HKEY_CURRENT_USER\Software<wbr />\Microsoft<wbr />\Windows\C<wbr />urrentVers<wbr />ion\Explor<wbr />er\User Shell Folders-&gt;Cache<br />
<br />
ie check validity of folder used here (local to user, plenty of space, correct permissions).
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Also try this regsitry fix:
http://answers.microsoft.com/en-us/office/forum/office_2010-excel/microsoft-excel-cannot-open-or-save-any-more/ab1a73d9-1666-4cf5-a6a7-285d2004dd08 [http://answers.microsoft.com/en-us/office/forum/office_2010-excel/microsoft-excel-cannot-open-or-save-any-more/ab1a73d9-1666-4cf5-a6a7-285d2004dd08]

Suggestion is to:
1.run regedt32

2.check/change the value of

HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\User Shell Folders->Cache

ie check validity of folder used here (local to user, plenty of space, correct permissions).

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<div class="content wysiwyg-content">
Received this error when opening .XLS files in Excel 2013:<br />
<br />
&quot;MS Excel cannot open or save any more documents because there is not enough available memory or disk space&quot;<br />
<br />
We were able to get around it by opening the file properties and UNBLOCK'ing the file but would like to turn this feature off for good, as this does not set permanently for files opened that are not saved in a file location (i.e. Excel files attached to an e-mail).
</div>
</div>


Received this error when opening .XLS files in Excel 2013:

"MS Excel cannot open or save any more documents because there is not enough available memory or disk space"

We were able to get around it by opening the file properties and UNBLOCK'ing the file but would like to turn this feature off for good, as this does not set permanently for files opened that are not saved in a file location (i.e. Excel files attached to an e-mail).

MS Excel (2013) Opening Files from 97-2003 Not Enough Memory/Space Issue

Microsoft Excel topics include formulas, formatting, VBA macros and user-defined functions, and everything else related to the spreadsheet user interface, including error messages.

Microsoft Excel

Microsoft Office is an integrated suite of applications that includes Outlook, Word, Excel, Access, PowerPoint, Visio and InfoPath, along with a number of tools to assist in making the individual components work together. Coding within and between the projects is done in Visual Basic for Applications, known as VBA.

Microsoft Office

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.