I have a 2008 R2 terminal server with Citrix Xenapp 6.5 and office 2010 32 bit installed. This xenapp server is being used at a CPA business so they have tons of applications installed on the server but everything was functioning correctly until Google Chrome was installed. Once chrome was installed and they clicked on a link in outlook to open an email chrome would launch but with nothing in the window. I uninstalled chrome and now nothing happens at all once the link is clicked. I reinstalled chrome and it will open the link again in the blank window. I made IE the default browser and it asks to be set as the default every time I open IE, so for some reaseon it's not saving as the default browser. I installed Firefox and set it as the default browser, tested (no go) and uninstalled it, tested (no go). I followed the reg hack to change the "ChromeHTML" value to "htmlfile", which worked until I restarted the server. I have checked the reg and it has the correct settings. Anyone have any other ideas on this?