Outlook 2010 does nothing when replying

I have one user in my organization who will occasionally attempt to reply to an email, but nothing happens. He has no mail rules configured; after restarting Outlook the functionality returns. I performed a repair and a reboot, and am currently waiting to see if these steps resolved the issue. In the meantime, what might be the cause of this? Thanks for your time.
neilbakkerAsked:
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webtechgalConnect With a Mentor Commented:
I have run into that issue when there is no reply email configured on the user account under change account/more settings /general/ reply email.
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