The best plan is to restart the SQL Server service when you have a window of inactivity. If that is not an option here are suggestions from MSDN:
How to shrink the tempdb database in SQL Server
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This tutorial will show how to configure a new Backup Exec 2012 server and move an existing database to that server with the use of the BEUtility.
Install Backup Exec 2012 on the new server and apply all of the latest hotfixes and service packs. The…