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Secondly, take extra care when getting advice on backups. If you suffer a failure and your business ends up having to close due to poor advice on backups you wont get any compensation from the people giving advice.
Anyway, we need some details to be able to offer you any useful advice. please let us know the following:
Internet line speed (up & down)
Number of servers, their OS, criticality & estimate of their disk usage
Applications & their data size (eg Exchange 2007 - 45GB mailbox DB)
Thanks.