Backup Hard Drive Removal

you can use some NAS with hot swap feature to do this

I was looking for a more specific device recommendation such as brand and model and experience with the device.

I second Andy's suggestion by using Imation,but you're capped at 1 TB and it ain't cheap.

My suggestion would be a hybrid of disk and tape personally.
Get a NAS for nearline storage and back up to tape for offline /off site.
Cheaper in the long run.

I have seen some other solutions when searching the internet, they are all a little expensive.  rind's approach may be the best option for small business that don't have a large budget.  I could purchase an external docking station for less than $100 and then the appropriate sized hard drive to interchange.  The only part I don't like is the exposed portions of the hard drive as this adds risk to the media.

I agree with andy's approach but it is more expensive.  It would reduce the risks of the exposed media parts from what I can tell.

The harddisk being "exposed" when you use a dock, doesn't matter at all. The platters in the disk aren't exposed.

I suggest you get several disks, not just one, as for a good backup strategy you need to be able to rotate between several of them.

agreed