SMTP server returned an error. 451 4.7.0 Temporary server error. Please try again later. PRX3

I have a some mail aggregation software on my Server2012/Exchange2013 box called Mailforward.

On occasion I receive the aforementioned error during the phase the application is passing emails onto the local receive connector.  I cant think what has changed within my environment that has recently induced this annoyance.  I don't recollect seeing it before, any idea's what is likely to be causing this?  And one more thing if you don't mind i have run the command.

Oh and for extra brownie points does anyone have any idea why my Exchange management Shell command

Set-ReceiveConnector "WILDSRV2012.gresidence.homeip.net\Default Recieve Connector" -MaxInboundConnectionPerSource 500

Appeared to be accepted but had no effect  and I still get the 421 4.4.3 error shown in the log?
log.txt
lukeglazebrookAsked:
Who is Participating?
 
Manpreet SIngh KhatraConnect With a Mentor Solutions Architect, Project LeadCommented:
I can only think of some replication or cache issue that cleared out and issue got fixed (more of a assumption)

- Rancy
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Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
What is the number of Recipients the Application is sending that email to at that moment ?

- Rancy
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lukeglazebrookAuthor Commented:
The application cycles through 6 different external account and forwards the mail to 6 different respective internal mailbox accounts.

Intriguing why do you ask mate?
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Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
You set the limit to 500 and what i know is that Applications do send emails to large DL's or with restrictions that can cause such issues for sure

- Rancy
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lukeglazebrookAuthor Commented:
Hi Rancy,

none of my SMTP target email address's are distribution lists.  The are all single alias email address's associated with individual Exchange mailboxes.

In a nut shell its simply 6 email accounts getting their email forwarded to 6 different email accounts.  Never had this issue at any point prior, the only thing I did was restore the Exchange box using Veeam (its a VM btw)
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Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
Is this Micorosft Exchange or some other technology as if Exchange we would simply try to move a mailbox and check

- Rancy
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lukeglazebrookAuthor Commented:
Yes Rancy appologies if I failed to highlight that.  The its a Exchange 2013 server on a Server 2012 box so pretty bleeding edge stuff.

The server aggregates from gmail and yahoo account and forwards onto its self i.e 127.0.0.1 aka the actual address 192.168.0.100.  I have attached the following picture since they say a thousand words :)
Capture.JPG
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lukeglazebrookAuthor Commented:
All was well prior and I cant think of any changes that may have effected things
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Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
So what else is working in between some firewall or something ?

Can the users send self email ?

- Rancy
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lukeglazebrookAuthor Commented:
I still have no idea what causes this problem but I do know that if left for several hours it seems to go away without any input from myself?  Does that help
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