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Access denied in Sharepoint / Sharepoint Designer even with Full Control account

I have an issue with our Sharepoint 2013 environment where one site gives access denied errors. I use an account which is member of the site admins, I can see the previously created lists etc but if I try to go to e.g. the Site Settings page I get an "access denied" error.
I tested with SP DEsigner what that would do but that basically does the same. I can create and delete a new list but I can't create any new pages.

E.g. I can't acces http://site/_layouts/settings.aspx

I even have run a powershell script to reset all permissions from the site's top level down.
Is this a permissions problem within the site or is this a folder permission (IIS??) of some sort?

If I create a complete new site in Sharepoint the problem does not occur.
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1 Solution
Have you checked the ULS logs for any obvious errors?  

I've seen strange permission errors if you've messed around with the SuperCacheUser and SuperCacheReader accounts - have you moved them from the "default" installation?
Mikex13Author Commented:
Ended up resetting all permissions from the top level down and that fixed the issue.
Mikex13Author Commented:
Needed to get this fixed asap. Read some artciles on the web regarding resetting permission from the top level down.
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