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Best enterprise antivirus software?

Hello, I would need an antivirus for smaller networks I maintain (5-15 computers in each + server or two). Something with no-nonsense approach, that is effective and fast.

Currently we use NOD, but I want to change it.

I hope someone could give a comparison and a selection of other offerings available.
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The only regret I have about Vipre's console is ESET's console is a little better.  I liked the ability to see much more about each machine through the console (which can be done with freeware tools, but it is nice that it was included).  Even down to which Windows updates have been installed.

You should be aware that the way in which Vipre displays threat levels is a little unsettling.  I had this discussion with their tech support.  After Vipre does a scan, if it has detected and even deleted a possible risk, i will display the level of the risk before the scan was completed.  So if a cookie is considered a low risk and you have your policies set to delete cookies on scans, When the scan is finished the console will display that the machine is at low risk (it is listed under "Highest Risk" - one assumes that means highest risk found before cleaning).  This is disconcerting to me, after all why list it at if the problem has been deleted?  Once you do another scan, if it comes up clean, then that designation goes away.
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Thanks all; regarding Vipre - they do have a corporate interface? I would really like something seamless. - Do i have to have an update server locally?

iconnectu - thanks for Re; - do I undestand well that the clients connect to the f-sec portal, and that I don't have to have an update server locally?
Not sure what you mean by 'they do have a corporate interface'?

As for having to have an update server locally no - basically the console can be installed on any machine(I was refering to server to mean a local machine that controls everything)

Way it works is you install the console - then from there you create 'policies' - each client is assigned to a policy and the policy determines the settings applicable to the client

For example I've 2 policies - Desktop and Laptop - so for my Desktop machines they all talk to the 'server' for updates, my Laptop machines I tell to get updates from the internet since they are on the road a lot...but its all controlled through the console either way...so flexible

The other product you could look at is GFI Cloud(Vipre is what they run as AV) but its cloud based, the 'console' is in the cloud and you install small client on your machines onsite - they then are controlled from the web interface that you can access anywhere...so another way to do the same thing except its 'cloud based'...

http://www.gficloud.com/
I've had the Vipre console installed on both server an workstation it can work either way.  There is also a way to move the console from one machine to another ( you need access to the original machine in order to set the policies to ask for updates from another console).  The clients can communicate with the console even if you cannot normally remotely access those machines (other than RDP). You can also preconfigure installers for different policies and operating systems (win32, win64, Android, iOS).

Remember to try before you buy.
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Guys, thanks a lot for this. I will now close the Q and award points, and research a bit on my own.

I've contacted F-Secure for distribution, and also have to do so for Vipre, to see what are their terms.

Thank you.