I've been working on this for too long now. I have 2 iphone users windows server 2008 R2, Exchange 2010 who cannot get their iphones connected using exchaneg activesync. One of the iphones was working for several months and one is brand new. I have a android device that is working with activesync. The problems started when the Exchange transaction logs filled up and their w3wp.exe processes were consuming a ton of cpu. I finally have that straightened out. Their certificate has all the correct names, autodiscover is working properly, DNS is working, I have deleted and recreated a few of the iis 7.5 virtual directories, checked authentication and permissions. I have been at this for 3 straight days and a bunch of hours prior to that. The activesync broke for good last Wednesday right after some strange certificate prompts started in outlook 2007 and above which I believe was related to autodiscover. Like I said, i think I have all of that squared away. The exchange remote tests pass. When I sign into accoutn on the phone, it spins forever verifying account and then eventually fails. I tried a decent number of things on the phone-reset network settings, delete and recreate the account more times than I can count, tried a brand new test user who worked the first time I connected it and then after connecting the problem users successfully one time, they all broke again. I'm stuck Any help would be appreciated.