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ESMTP #550 Cannot relay. Mailbox not available

Posted on 2013-06-03
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Last Modified: 2013-06-10
Hello. I need to figure out why I'm getting the following errors from my SBS 2008 / Exchange 2007 server today. Both messages to the "af.mil" are getting bounced with this error message. Additionally, I have successfully sent test messages to these addresses from another e-mail server.

Diagnostic information for administrators:
 
Generating server: SBSERVER.?????.local
 
?????@?????.af.mil
ESMTP #550 Cannot relay. Mailbox not available ?????@?????.af.mil ##
 
?????@?????.af.mil
ESMTP #550 Cannot relay. Mailbox not available ?????@?????.af.mil ##
 
Original message headers:
 
Received: from SBSERVER.?????.local ([?????]) by
 SBSERVER.?????.local ([?????]) with mapi; Fri,
 31 May 2013 09:13:05 -0700
From: ????? <?????@?????.com>
To: "?????"
        <?????@?????.af.mil>
CC: "?????" <?????@?????.af.mil>,
        ????? <?????@?????.com>, ?????
        <?????@?????.com>
Disposition-Notification-To: ????? <?????@?????.com>
Return-Receipt-To: <?????@?????.com>
Date: Fri, 31 May 2013 09:13:04 -0700
Subject: TO0012 Transformer progress report labeled #11
Thread-Topic: TO0012 Transformer progress report labeled #11
Thread-Index: Ac5eGZYtw5H3o98BSXmFG/jUOnLG9w==
Message-ID: <43F2D0F2E1ACC9439211363B909F81BADBE510D42B@SBSERVER.calpropaint.local>
Accept-Language: en-US
Content-Language: en-US
X-MS-Has-Attach: yes
X-MS-TNEF-Correlator:
acceptlanguage: en-US
Content-Type: multipart/mixed;
        boundary="_004_43F2D0F2E1ACC9439211363B909F81BADBE510D42BSBSERVERcalpr_"
MIME-Version: 1.0

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Any ideas?

Thank you in advance!
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Question by:SkinnerTech
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9 Comments
 
LVL 18

Expert Comment

by:suriyaehnop
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Please provide the details on your Send-Connector
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Author Comment

by:SkinnerTech
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It's using the Hub Transport server role:

FQDN = remote.?????.com
Network = Use DNS "MX" records to route mail automatically
[  ] Enable Domain Security (unchecked)
[  ] Use the External DNS Lookup settings on the transport server (unchecked)

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Exchange is not my forte, so bear with me. If you need anything else please let me know.
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LVL 18

Expert Comment

by:suriyaehnop
Comment Utility
How about Address Space tab on "Send Connector"
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Author Comment

by:SkinnerTech
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Type = SMTP
Address = *
[ X ] Include all subdomains (checked)
Cost = 1

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Assisted Solution

by:mmahaek
mmahaek earned 250 total points
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99% of the time I see this error, it turns out to be the recipients spam filter blocking the message.
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LVL 13

Expert Comment

by:Mark Galvin
Comment Utility
Hi

What application are you using to send the email that is bouncing back?

The error 'ESMTP #550 Cannot relay. Mailbox not available ?????@?????.af.mil ##
 ' is stating that it cannot relay, which normally is your exchange box telling you that something is trying to use it as an smtp relay which is turned off be default

Just an idea

Thanks
Pappaslim
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LVL 13

Expert Comment

by:Mark Galvin
Comment Utility
http://www.gordano.com/kb.htm?q=475
Might help

Thanks
Pappaslim
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Author Comment

by:SkinnerTech
Comment Utility
Hey Guys

Thanks for the help. We are using Outlook 2010 from within the domain to send the mail. Also, just to clarify - the problem only exists with these two recipients.

What do you guys think?
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Accepted Solution

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Simon Butler (Sembee) earned 250 total points
Comment Utility
Looks to like it is a problem with the recipients server blocking the message for some reason. The fact that your server is in the NDR just means that is the server that generated the NDR, not the server that caused it. I don't think there is anything wrong with your server.

Simon.
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