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Create a GPO that includes that 4 computers (not the users) and deny them acess to that particular application.<br />
The GPO will be:<br />
<br />
Computer configuration &gt;&nbsp;Windows Settings &gt;&nbsp;Security Settings &gt;&nbsp;Software restrictions Policies &gt;&nbsp;Additional Rules<br />
Right click and choose NEW HASH RULE<br />
Then choose the path to the EXE of the program you want to block and choose NOT ALLOWED.<br />
<br />
Apply this GPO to the 4 computers.
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Create a GPO that includes that 4 computers (not the users) and deny them acess to that particular application.
The GPO will be:

Computer configuration > Windows Settings > Security Settings > Software restrictions Policies > Additional Rules
Right click and choose NEW HASH RULE
Then choose the path to the EXE of the program you want to block and choose NOT ALLOWED.

Apply this GPO to the 4 computers.

<div>
Have a look at below link too:<br />
<br />
Restrict applications to certain users:<a href="http://social.technet.microsoft.com/Forums/windowsserver/en-US/ca63fb02-5821-4866-ae88-c79de8aeed90/restrict-applications-to-certain-users" rel="ugc nofollow">http://social.technet.microsoft.com/Forums/windowsserver/en-US/ca63fb02-5821-4866-ae88-c79de8aeed90/restrict-applications-to-certain-users</a><br />
<a href="http://www.informit.com/articles/article.aspx?p=366893&seqNum=7" rel="ugc">http://www.informit.com/articles/article.aspx?p=366893&seqNum=7</a>
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Have a look at below link too:

Restrict applications to certain users:http://social.technet.microsoft.com/Forums/windowsserver/en-US/ca63fb02-5821-4866-ae88-c79de8aeed90/restrict-applications-to-certain-users [http://social.technet.microsoft.com/Forums/windowsserver/en-US/ca63fb02-5821-4866-ae88-c79de8aeed90/restrict-applications-to-certain-users]
http://www.informit.com/articles/article.aspx?p=366893&seqNum=7 [http://www.informit.com/articles/article.aspx?p=366893&seqNum=7]

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<div class="content wysiwyg-content">
I have a situation.<br />
<br />
We want to block access to an application for users, but only when they log onto certain Terminals<br />
<br />
At my site the users will be running their desktops via Remote Desktop, either accessing it from PC's or Thin Clients.<br />
<br />
I need to prevent a program from being run when any user logs onto one of 4 thin clients in particular for security reasons. &nbsp;If that user logs onto any other machine they need to be able to run the app.
</div>
</div>


I have a situation.

We want to block access to an application for users, but only when they log onto certain Terminals

At my site the users will be running their desktops via Remote Desktop, either accessing it from PC's or Thin Clients.

I need to prevent a program from being run when any user logs onto one of 4 thin clients in particular for security reasons.  If that user logs onto any other machine they need to be able to run the app.

Group Policy - App Restriction - By Device - By User

This topic area includes legacy versions of Windows prior to Windows 2000: Windows 3/3.1, Windows 95 and Windows 98, plus any other Windows-related versions including Windows Mobile.

Windows OS

Active Directory (AD) is a Microsoft brand for identity-related capabilities. In the on-premises world, Windows Server AD provides a set of identity capabilities and services, and is hugely popular (88% of Fortune 1000 and 95% of enterprises use AD). This topic includes all things Active Directory including DNS, Group Policy, DFS, troubleshooting, ADFS, and all other topics under the Microsoft AD and identity umbrella.