we are running XenApp 5.0 and it's patched with rullup 1 and one more hotfix which is dated some time back in 2011 ( October) ; we have some issues with this server and I noticed there are whole bunch of hotfixes available . we noticed that the server becomes unresponsive every once in a while and needs a reboot.
It's a bit confusing ; do I need to install ALL of these hotfixes ? or just the ones that I think
can be related to performance issues ? what is the best practice here?