Outlook 2010 - Occasional "Not Responding"

Hello All,

Having some Outlook issues again with a user.. and I am stumped, though I know it probably has to do with the database size? (my guess)

Setup :

Exchange 2007
User - Outlook 2010

Issue :

When user closes out of Outlook and restarts, it hangs and goes to "not responing" for at least 5 minutes.  Once started, it works fiine for the most part.. but then occasionally a new email would come through, and Outlook would hang again with "not responding".

-Local OST is 48GB.  
-User has mounted (2) additional mailbox to Outlook Profile

When I click on Send and Receive, it goes through the first process "sending..." but the second process it just hangs..

Any help is greatly appreciated.

Note : This a new Desktop setup with SSD about a month ago.
Who is Participating?
I wear a lot of hats...

"The solutions and answers provided on Experts Exchange have been extremely helpful to me over the last few years. I wear a lot of hats - Developer, Database Administrator, Help Desk, etc., so I know a lot of things but not a lot about one thing. Experts Exchange gives me answers from people who do know a lot about one thing, in a easy to use platform." -Todd S.

AdrienneSperberTech Support CoordinatorCommented:
Start it in safe mode, if it works fine, try disabling add-ons
Coupee46Author Commented:

Thank you.  I will give that a try! Any other suggestions.. :)
Md. MojahidCommented:
Start Outlook by using the /CleanAutoCompleteCache switch.

Experts Exchange Solution brought to you by

Your issues matter to us.

Facing a tech roadblock? Get the help and guidance you need from experienced professionals who care. Ask your question anytime, anywhere, with no hassle.

Start your 7-day free trial
Coupee46Author Commented:
Haven't had chance to test, but best answer..
It's more than this solution.Get answers and train to solve all your tech problems - anytime, anywhere.Try it for free Edge Out The Competitionfor your dream job with proven skills and certifications.Get started today Stand Outas the employee with proven skills.Start learning today for free Move Your Career Forwardwith certification training in the latest technologies.Start your trial today

From novice to tech pro — start learning today.