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Platform for designing a database-driven website, compatible with mobile devices

I am developing a database-driven website, intended to be compatible with mobile devices.

I started developing it 5 years ago using .NET / SQL Server, and then layered AJAX on it to arrive at better query response time.  However, queries currently run slow, and it's not compatible with mobile devices.  It's now time for a re-design, utilizing latest technologies and frameworks.

Are there any particular platforms / frameworks that are currently well suited for database-driven web applications, that also work well on mobile devices?
Web DevelopmentResponsive WebDatabases

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8/22/2022 - Mon

and it's not compatible with mobile devices
What database you use has nothing to do with the device used to view the webpages.
If queries are running slow then you need to optimise your queries, db and maybe your db structure

Optimizing the DB is certainly part of the plan.  But this question is specifically regarding the web platform.  For example, currently my .NET listboxes do not show up on mobile devices, iPhone is not able to render the listboxes unless the user taps the listbox first, which adversely affects usability.  I hear something like Twitter Bootstrap provides good compatibility with mobile devices for web controls.  
Is this a preferred platform?  Are there others?

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