Configuring Cisco IronPort Behind F5 Load Balancer

We presently have F5 Load Balancer accepting Email Traffic and then forwarding to 2 TMG/Forefront/Exchange Edge servers for processing through a VIP.  We are planning to implement Cisco IronPort as  a replacement for the Forefront protection, however reading the documentation shows that the IronPort must be direct to Internet, is this true, and will we be not able to to use the F5 load balancers in front of the IronPorts?
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fireguy1125Asked:
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Sudeep SharmaTechnical DesignerCommented:
>>>however reading the documentation shows that the IronPort must be direct to Internet, >>>is this true, and will we be not able to to use the F5 load balancers in front of the >>>IronPorts

Assuming when the F5 Load Balancer in place Ironport would see only its IP address as the source of receiving emails, there are following dis-advantages:

Yes it is true. You won't be able to take the full advantage of the Ironport AntiSpam techiniques like:
Senderbase IP reputation services which blocks the connection from IP addresses based on its reputation.
Ironport wont be able to put restrictions on the number of connections made by the IP addresses per hour.
The number of mails per IP per hour limits.
You could not block the Source IP address.
You could not allow the particular Ip address to send the email and bypass spam filtering.

Unless F5 work in the transparent mode and there is no additional hop added to the network layer and Ironport could see the external IP connecting to it.

Sudeep
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