W2012 No such interfaced supported

I had just finished installing SQL Server 2012 onto my W2012 server and suddenly all of my desktop icons vanished. I tried logging out and back in and the icons appeared but when I click on any of them I get the message "No such interface supported". I have had others user try to login and now they all have the same problem. I cannot even run Windows Explorer. Is there anything I can do? My thought now is to trash W2012 and go back to W2008R2. Any suggestions on how to get W2012 functional again?
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Ayman BakrSenior ConsultantCommented:
This clearly indicates a corruption in the system files. Although the following is related to Windows 7, the methods should be well valid for fixing/restoring a 2012 system:


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rwheeler23Author Commented:
We brought Microsoft in on this one. What had happened is a developer had RDP'd into the server while an admin was also RDP'd into the server. The admin had changed the security rights on a leaf of the registry. The second that happened, everyone's desktop was hosed with the exception of the admin. I took Microsoft three support call sessions to get everything back to normal. I had just been in doing the SQL install while this was happening.
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Windows Server 2012

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