I was trying to clean an XP desktop that was heavily infected. I ran Superantispyware on it and Malwarebytes which helped, but didn't clean out the main problem.
I ran TDSSKiller and selected the additions options it listed. After it rebooted and started the scan, it found a rootkit and four other files. I selected delete on all five files. The four non-rootkit files were marked as locked.
After it rebooted, I received the BSOD on boot. I tried going into safemode, but right after I selected it, the same BSOD appeared.
I'm assuming the four locked files were system files no longer exist and caused the BSOD.
I would normally just do a clean install, but this desktop has an accounting app on it and I don't think there was a backup taken.
What's the safest way to get it running again without messing up the accounting app and other data they may have on it?