haroldcw73
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Citrix Receiver could not open specified profile file
Running Citrix XenApp 6.5 Farm, when users launch a streamed application, Citrix Receiver returns error "could not open specified profile file. check the profile path specified". Path permissions have been checked, and some users have no problem launching the application. Roaming profiles have also been cleared and permissions reset. This occurs across all servers in Worker group, and can be repeated by specific users.
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Check this
Troubleshooting Application Streaming Issues
http://support.citrix.com/article/ctx113304
Hope that helps :)