Generating event ID 15000 Source; BlackBerry MDS Connection Service for every Minute

Hi
We are getting a lot of Below Events to our Black Berry Server continually after every 1 minute.

Source       BlackBerry MDS Connection Service
Category       None
Event ID       15000
User       N/A
Description       <2013-10-22 07:35:08.089 EDT>:[2379]:<MDS-CS_ServerName_MDS-CS_1>:<ERROR>:<LAYER = SCM, BMS: database notifyEventsDisconnectEvent failed rc=1>

Also we are getting below Error Event for same  server.
Source       BlackBerry MDS Connection Service
Category       None
Event ID       15000
User       N/A
Description       <2013-10-22 07:35:37.402 EDT>:[2385]:<MDS-CS_ServerName_MDS-CS_1>:<ERROR>:<LAYER = SCM, com.microsoft.sqlserver.jdbc.SQLServerException: The TCP/IP connection to the host SERVER01, port 4412 has failed. Error: "Connection refused: connect. Verify the connection properties, check that an instance of SQL Server is running on the host and accepting TCP/IP connections at the port, and that no firewall is blocking TCP connections to the port.".>

&

Source       BlackBerry MDS Connection Service
Category       None
Event ID       15000
User       N/A
Description       <2013-10-22 07:25:11.640 EDT>:[2331]:<MDS-CS_ServerName_MDS-CS_1>:<ERROR>:<LAYER = SCM, com.microsoft.sqlserver.jdbc.SQLServerException: The TCP/IP connection to the host SERVER01, port 4412 has failed. Error: "connect timed out. Verify the connection properties, check that an instance of SQL Server is running on the host and accepting TCP/IP connections at the port, and that no firewall is blocking TCP connections to the port.".>

Request you to please suggest the Solutions for same….
Please refer this as High Importance.

Thanks In Advance

Thanks,