I work for a small company and we send out mass emails to our patients approximately once every 6-8 weeks advertising new trials. They go out to about 2000 people.
A few weeks ago we found that our domain had been added to Trend Micro's "spammer list". My guess is that enough of our customers hit the "report as spam" button on their trend anti spam protection software to get us on the list. We contacted our ISP and were able to get the domain removed from the list but it did take almost a week.
We haven't sent out any more because we're a little concerned about the "reputation" of our primary domain. In our business, we basically have two sets of customers because we run trials for Rx companies. So, we work hard to acquire the trials from those companies and then we recruit our "other customers", which are the Patients who participate in the trials.
Having a good reputation with our trial sponsors is obviously extremely important to our company, and it's frankly a little embarrassing to have our emails blocked as spam when we're trying to communicate with them. So, I had the idea to get a totally separate domain to do these bulks emails in order to keep the reputation of our primary domain clean.
My question is just to ask for an expert opinion about whether this is the right thing to do.