Up until the night before last we were running a XenApp 6.5 server on Windows 2008 R2 servers using Citrix Access Server and the Web Interface with no issues using Gateway Direct as the default access method. Came in yesterday morning and no one could access the farm, as in no credentials were valid. I changed the access method to direct and the XML transport to HTTP from SSL Relay and internal users can access, but external users can't. I've unregistered and registered the xml service on all of the XenApp servers. I've ran a repair on the sites. I've re-run the configuration. Can't figure this one out. Any ideas?