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Email fails to specific domain with '421 4.2.1 Unable to connect'

Posted on 2013-11-14
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Last Modified: 2013-11-19
We have a simple Exchange 2010 single server setup. Everything has been running fine for years. We have one domain that we are attempting to send an email to that fails. All other emails are flowing fine. The error in the queue is:

451 4.4.0 Primary target IP address responded with: '421 4.2.1 Unable to connect' Attempred failover to alternate host, but did not succeed. Either there are no alternate host, or delivery failed to alternate hosts.

The last successful message to this domain was about 8 weeks ago. I can do an nslookup on the MX records and see them there. I have done an mxtoolbox.com backlist check on my domain and that is coming back fine.

Ideas?

Thanks
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Question by:GlennCameron
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Expert Comment

by:Dave Baldwin
ID: 39649846
The usual thing is to 'telnet' to their mailserver and see if it responds.  Or if there is a contact email address, you could try to send them an email thru Yahoo or Gmail to see if they're still there.
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Author Comment

by:GlennCameron
ID: 39649881
I cannot telnet to the mail server. I get 'Connecting to xxxx' then 'Connect failed'.
FYI the domain is a US state government department so they're still there :-)
Their IT is saying that's its an issue on our server.

Thanks
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Assisted Solution

by:lindento
lindento earned 100 total points
ID: 39649906
Hi,

check that your DNS is resolving the MX records correctly, easy check for this is do an mxtoolbox.com mx check.

If you try to telnet their listed mx on port 25 and can't reach it,
you need to rule out firewall on your end blocking access to their IP.
Also try telnetting to that mailserver from outside your company network(effectifly testing if firewalls are limiting you)

Best Regards
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Author Comment

by:GlennCameron
ID: 39649919
I have done the mxtoolbox.com mx check and they appear to be correct. Was going to try the telnet from home tonight.

Thanks
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Author Comment

by:GlennCameron
ID: 39652198
I cannot telnet to the server either inside my corporate network or at home. Two completely different ISPs and of course no firewall at home.
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Accepted Solution

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Dave Baldwin earned 400 total points
ID: 39652331
Sounds to me like that server is not working or available anymore.  The fact that it is still listed in DNS does not mean that it is available.  You would have to find an alternate method of contacting them to find out what is happening.
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Author Closing Comment

by:GlennCameron
ID: 39661148
The destination company finally admitted that they were blocking the traffic.
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Expert Comment

by:Dave Baldwin
ID: 39661187
Interesting.  Did they say why?
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Author Comment

by:GlennCameron
ID: 39661195
Spam attack from somewhere in China so they have put a lot more restrictions in place. You would of thought that they could have told us that when we first raised the issue!
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