5.0.0 smtp; 550 #5.1.0 Address rejected.> #SMTP#

I am getting this error. Please advice.
THank you

Diagnostic information for administrators:

Generating server: server-9.bemta-12.messagelabs.com

tmxmailsmtp.telmex.com #<tmxmailsmtp.telmex.com #5.0.0 smtp; 550 #5.1.0 Address rejected.> #SMTP#

Original message headers:
Who is Participating?
SeanConnect With a Mentor System EngineerCommented:
we will need more information...looks like server-9.bemta-12.messagelabs.com is blocking the message because it is not a valid sender but what are you trying to do here???
claudiamcseAuthor Commented:
Trying to fix the issue with that NDR. Users getting NDR mentioned when trying to send to that email address
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