I have come across an unusual issue with our CRM client, at the moment this issue is only occurring on one users computer. The user can connect to CRM and select and of the CRM folders from within the CRM Dynamics folder however clicking on and of the information displayed i.e. a Lead would usually open a new window containing the Laead information, however clicking on a Lead, opportunity, contact etc... on this particular machine does not launch IE and noting appears to be happening...
This appears to be an an unusual issue and all users here are running the same version of MS office 2010 sp1 using the 32bit CRM outlook client and version 10 of IE, all has been working well for each user and this issue has just randomly surfaced today.
Note, the user can still connect to the CRM directly via IE and there is full functionality doing it this way, so my thoughts are that the issue is related to the outlook client.