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Yes perfectly acceptable to have a mix of versions in a clustet .<br />
<br />
As you are aware ESXi 4.1 can only host version 4.0 and 7.0 VMs.<br />
<br />
5.1 can host 4.0, 7.0 8.0 and 9.0 so be careful with vMotions
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Yes perfectly acceptable to have a mix of versions in a clustet .

As you are aware ESXi 4.1 can only host version 4.0 and 7.0 VMs.

5.1 can host 4.0, 7.0 8.0 and 9.0 so be careful with vMotions

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hanccocka;<br />
5.1 can host 4.0, 7.0 8.0 and 9.0 so be careful with vMotions<br />
what will happen if i try to vmotion from esxi5.1 to ver 4.1 by accident?<br />
Will it cause any damae to the VM or it will not vmotion?
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hanccocka;
5.1 can host 4.0, 7.0 8.0 and 9.0 so be careful with vMotions
what will happen if i try to vmotion from esxi5.1 to ver 4.1 by accident?
Will it cause any damae to the VM or it will not vmotion?

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is it possibe to have mix ver of esx in a single cluster, I hav etwo ver4.1 esx hots and 4 ver5.1 esxi hots?<br />
I know the vms hardwae are not same. that the reason I would like to have two for ver4.1 and the rest5.1 &nbsp;<br />
Can I keep it like that? otherwise i have to spend money on licenses.
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is it possibe to have mix ver of esx in a single cluster, I hav etwo ver4.1 esx hots and 4 ver5.1 esxi hots?
I know the vms hardwae are not same. that the reason I would like to have two for ver4.1 and the rest5.1  
Can I keep it like that? otherwise i have to spend money on licenses.

mix ver of esx in a cluster.

The Microsoft Legacy Operating System topic includes legacy versions of Microsoft operating systems prior to Windows 2000: All versions of MS-DOS and other versions developed for specific manufacturers and Windows 3/3.1, Windows 95 and Windows 98, plus any other Windows-related versions, and Windows Mobile.

Microsoft Legacy OS

VMware, a software company founded in 1998,  was one of the first commercially successful companies to offer x86 virtualization. The storage company EMC purchased VMware in 1994. Dell Technologies acquired EMC in 2016. VMware’s parent company is now Dell Technologies.

VMware has many software products that run on desktops, Microsoft Windows, Linux, and macOS, which allows the virtualizing of the x86 architecture.  Its enterprise software hypervisor for servers, VMware vSphere Hypervisor (ESXi), is a bare-metal hypervisor that runs directly on the server hardware and does not require an additional underlying operating system.