Exchange Server 2003 - No Outgoing Email - Messages Stuck in Queue

Yesterday, our users started to receive Delivery Delay notices for the outgoing email that they had sent.  Today, the problem is continuing.  I started to look into it and noticed within the Exchange System Manager the queue has about 155 items in it and the number is not decreasing.  When I click on one of the items, it states at the bottom of the System Manager that "The remote server did not respond to a connection attempt."  

I found a suggestion online to stop the SMTP server, go into the Exchsrvr\Mailroot\vsi 1\Queue directory, cut / paste the files into another location and then start the SMTP server up again.  Then try sending an email again to see if it goes through.  I tried this but even after cutting / pasting the files from the Queue folder, the Exchange System Manager still shows 155 items in the queue for processing.

I am at a loss on what to do here to get outgoing emails working again.  Any help is greatly appreciated!
csimmons1324IT ManagerAsked:
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csimmons1324Connect With a Mentor IT ManagerAuthor Commented:
I believe that I was able to get the problem resolved.  For the SMTP Connector, I had the Forward all mail through this connector to the following smart hosts as the following: smtp01.abc.com.  Within the Advanced Delivery settings of the SMTP Virtual Server, I had the smart host set to smtp02.abc.com.  As soon as I changed smtp02.abc.com to smtp01.abc.com it started working.  

I am assuming TotalDefense stopped using smtp02.abc.com as a smarthost and that is what was causing the problems?!?!  This may be a dumb question but why are smart hosts set in two different locations with Exchange?

Sorry for what may be dumb questions but I am learning Exchange as I go.

Thanks again!
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csimmons1324IT ManagerAuthor Commented:
FYI....incoming email seems to be working fine.
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Simon Butler (Sembee)ConsultantCommented:
If the messages have been moved then they should be gone from the queue.
How much disk space is on the server?

Are you using a smart host for email?
Do you have an SMTP Connector configured?

Simon.
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csimmons1324IT ManagerAuthor Commented:
Yes, I am using a smarthost.  We currently use TotalDefense to filter / monitor our outgoing email.  A SMTP Connector is also configured.  The C: partition has about 3.5 GB of space left.  The E: partition that holds the datbase and logs has about 26 GB.

This is only happening for email messages leaving our domain.  All internal email messages seem to be working fine.

Nothing has changed in terms of settings.  As stated early....this problem just started happening out of the blue.  

As for the messages still showing in the queue...I am not sure why they are there when I moved them out of the directory.  Also, there were only a handfull of files within the Queue directory....not the 155 that is being shown in the System Manager.
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Simon Butler (Sembee)ConsultantCommented:
You shouldn't have a smart host on the SMTP virtual server at all. That value should be blank. If you need to use a smart host configure it on the SMTP Connector ONLY.

Simon.
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csimmons1324IT ManagerAuthor Commented:
Solution worked.
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