I am testing an implementation of the Software Restriction policy in Group Policy. I have opted for the default of Restricted and then creating exceptions for permitted applications paths. I have allowed Program Files, Program Files (x86), *.lnk, and the path to our EHR program. All seems to work fine when testing. I can open Internet Explorer, MS Office, our EHR, and any other programs loaded in those paths. However, there is an "integration" in our EHR that basically just launches IE and passes the patient name in the URL to the database in the cloud so that we can pull up that patient's imagery. When the GPO is not applied, this works as expected. When the GPO is applied the application launch fails but no message is given as to why. I know the GPO is working because I have tested by trying to launch Process Explorer out of its own directory and it was blocked by policy (as expected). Is there a known issue with permitted applications launching other permitted applications but failing? Has anyone encountered this when they setup similar policy restrictions? I've even tried hashing IE and allowing it that way but there is no change in the behavior.