Unable to change permissions on program files folder - windows xp

I have a domain PC running XP.

I'm logged in as the domain admin. The domain admin is in the local admin group on the PC

I cannot change the permissions through the security tab  on the program files folder (though I can change other folders below it) Error  - Security - 'Unable to save permission changes on program files. Access is denied'

I have also tried logging in as the PC's local admin but I still can't add domain permissions to the folder.

Why can't I add permissions on the program files folder?
APC_40Asked:
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BlueComputeCommented:
Sounds like the folder has damaged permissions - have you tried taking ownership of the folder as the "Administrators" group on the "Owner" tab of advanced security settings?
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APC_40Author Commented:
A certain folder was blocking the permissions
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