Ounce of pervention is a pound of cure!
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It is all or nothing.
The most you can do is run setup, let it go through the prerequisites and if there is a problem it will tell you. However once you have done it, there is no going back.
What makes you think there is a problem? I cannot remember the last time I had a problem with prep going back to the days of Exchange 2000.
If you don't have any custom domain schemas it is relatively trouble free.