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Outlook error opening and a url General Failure: The URL was

Outlook 2010 opened all URLs in Firefox even though my default browser was safari. I have cleaned Windows 7 thoroughly, Malwarebytes, Superantispyware, hijack this etc.

Repaired Office 2010, and I still get the error:
General Faulure  the url was "www.mydomain.com" application not found

File associations, and the default programs list safari as the default browser.
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Gareth Gudger
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This article discusses problems opening Hyperlinks in Outlook 2010 and 2013.
http://supertekboy.com/2013/02/07/your-organizat/

It was an issue with the default browser.
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ASKER

That didn't work.

I noticed that resetting internet explorer that I get a red x on applying computer settings.

I've tried running as administrator, and in safe mode.  Still cannot reset. This  may be related.
What happens if you uninstall Safari?
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Same error in Outlook and Cannot reset internet explorer still.
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cnl83
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ASKER

Solved it myself