Uploading files using Intranet not saving files

Note: The same Code works in a hosted environment for a web site I have also on windows platform.

My problem is using the same code for an Intranet.

Server: MS Win Svr 2012
Using IIS with php installed
Uploading software: plupload

When using PLUPLOAD I can select the files and when I choose to upload them I get a message "HTTP Error", no other explanation.

I immediately though it was permission on location saving files to (but can't see anything wrong) as write permissions have been applied.

Here is a sample of my structure where files are being saved:
Intranet
   ----uploads
        ----work
        ----docs
        ----stuff

The uploads folder is set with write permissions so therefore all subfolders inherit the same permissions.

Any assistance, grateful.
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AIGSNetwork AdministratorAsked:
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Dave BaldwinFixer of ProblemsCommented:
On earlier versions of IIS, I had to give the IIS user (IUSR?) and the 'Everyone' user write permissions to get that to work.
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AIGSNetwork AdministratorAuthor Commented:
Using IIS8 on Win Svr 2012

IUSR, Everyone and IIS_IUSERS have all be set with write permissions.
Same problem.
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AIGSNetwork AdministratorAuthor Commented:
This was part of the solution and led me to other issues that required attention.
Thanks.
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Dave BaldwinFixer of ProblemsCommented:
You're welcome, glad to help.
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