Microsoft Server Anti-Virus Anti-Malware Protection Recommendation

I am looking for recommendations on Windows server protection software.  I run a small number MS SQL Servers and Windows Application Servers on Amazon EC2 and on Server Farms.  I'd really prefer to standardize.  

It wouldn't be an issue, but I was running Malawarebytes anti-malware and my number one server got infected and we had to rebuild from I am on the hunt for something more reliable that doesn't bog down the system or take a ton of maintenance.

For what it's worth we send all our email via SendGrid, and none of the servers currently handle incoming email.
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JohnBusiness Consultant (Owner)Commented:
Agree with personal preference. Make sure what you select is paid, commercial and mainline.

I use Symantec Endpoint Protection for all my client Servers and Workstations. It works fine, does not use a lot of resource (except logs sometimes) and does not conflict with most common software in use today.
Just a personal preference, but I use ESET Endpoint Security, and Endpoint Antivirus (where I don't need the extras).

Very easy on resources and can be managed remotely.

So far, so good with this.

Again, this is a personal preference but probably one you should read up on too.
btanExec ConsultantCommented:
indeed the key consideration is not the anti-malware capability only but the central mgmt, visibility of client state at single swift demand, and signature patch deployment quickness. Having multi AV in segment or machine is not really managable and going to cause even more issues in interoperability and operational cost..

However, just to sketch the thinking to have multi AV still achievable (regardless the endpoint existing AV) but still be able to achieve multi AV scan all managed by single security endpoint (not AV associated) client e.g. metascan @

Metascan is a server application with a local and network programming interface that allows customers to use multiple antivirus engine scanning technologies in their security architecture. Metascan packages can be delivered with a variety of fully incorporated and licensed antivirus engines to deliver fast, scalable, and reliable content scanning to protect against viruses, spyware, and other malware. The highly flexible APIs provide the customer with numerous programming options for integrating Metascan into existing or custom build security systems.
zerogravityAuthor Commented:
I do appreciate all the comments.  Interestingly going to the Metascan site showed that at least one anti-virus software was significantly better than the others, but they did not reveal which one.  That would be nice to know.
JohnBusiness Consultant (Owner)Commented:
@zerogravity - Thanks for the update and I was happy to help.
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