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Single or multiple Exchange servers?

Lwaugh
Lwaugh asked
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Last Modified: 2014-03-13
I am looking for some info on best practice for a global Exchange setup.  My company has close to 40 offices in 35+ countries.  I work in IT in the US and our group IT Manager is in Europe.  Their consultant recommends we use a single Exchange server for the entire group.
We have about 1000 mailboxes.  

To me it makes more sense to have regional servers with the mailboxes for the users in that region.  I think it should make backups more manageable and local administration easier.  Not to mention the importing into Exchange.  (using an IMAP/POP solution right now)

I've done some reading on Microsoft best practices for deployment, but can't seem to find anything about this scenario.  
Any help would be appreciated.
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