Asa 5540 version 7.0(7) in front of exchange 2003 enterprise with the latest service pack, and GFI antispam box, queue builds up almost on daily basis, and we have to reload the firewall in order the get the email flowing, it works for a day then it happens again.
no changes have happened since this started , we have relay taken care of already long time ago and we are good in that aspect. Also, smtp fixup is unchecked on the firewall.
I'm the only administrator in the company, I have not made any changes for the past 6 months not even patching the exchange server. and everything was working fine until 4-5 days ago.