Mail address block - Exchange 2010

what is the best way to block the mail box from the exchange 2010 . can i block that from the exchange application level  or ISP level -spam filter ?
curAsked:
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Simon Butler (Sembee)ConsultantCommented:
By gateway I mean whatever receives the email from the internet. If your MX records are pointing at an IP address that resolves to Exchange, then you have to do it at Exchange.

Simon.
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Miguel Angel Perez MuñozCommented:
Thats depends,

For all users, on sender filtering: http://technet.microsoft.com/en-us/library/bb125179.aspx
For one user, on user properties: open exchange management console > recipient configuration > mailbox > select desired mailbox > right click > properties > mailflow settings > Message delivery restrictions > reject messages from > mark senders in following list > input email address > ok to all.
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curAuthor Commented:
this is external free email address to be block . not the internal address
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Simon Butler (Sembee)ConsultantCommented:
If you want to stop an address from emailing your users then it needs to be done at the gateway. Depends on how your email is routed. If you are using a hosted antispam service, then do it there, if you have something in front of Exchange, then do it at that point. If Exchange is the primary receiver then do it at the Exchange level.

However if the sender knows that you are blocking the message, then they may well just change the address being used. Therefore the best option is to use a transport rule to capture the message, then forward it to an distribution group that has no members. The message is then just dropped in to a black hole, no NDR returned.

Simon.
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curAuthor Commented:
you mean gateway  is the exchange . our exchnage box running in one box and use the ISP level published MX record with the primary receiver . we do not have any separate server for front or Edge Transport Server

one we have  Hub Transport servive and the rest of the common service on the same box .
any place I can find the mail routing setup details
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