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mail Queue Filling

we are seeing our mail queues filling with the error.

 432 4.2.0 STOREDRV.Deliver; Agent transient failure during message resubmission[Agent: Mailbox Rules Agent]

we restart the server and the mail will flow for a few minutes.  this is occurring to all mailboxes.

event Log
Log Name:      Application
Source:        MSExchange Extensibility
Date:          4/24/2014 11:45:42 AM
Event ID:      1051
Task Category: MExRuntime
Level:         Warning
Keywords:      Classic
User:          N/A
Computer:      P01EXC13WI08
Agent 'Mailbox Rules Agent' caused an unhandled exception 'StoreDriverAgentTransientException: Store Driver Agent was unable to send email.' while handling event 'OnDeliveredMessage'
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
    <Provider Name="MSExchange Extensibility" />
    <EventID Qualifiers="32772">1051</EventID>
    <TimeCreated SystemTime="2014-04-24T16:45:42.000000000Z" />
    <Security />
    <Data>Mailbox Rules Agent</Data>
    <Data>Store Driver Agent was unable to send email.</Data>
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2 Solutions
Can you check for disk space on the server, it looks more like a back pressure issue.
TheHapsAuthor Commented:
One item I have noticed it is not all e-mails
TheHapsAuthor Commented:
200 gb free on all disk the have Mail DBs
I am referring to location of your mail queue database
TheHapsAuthor Commented:
yes the que DB.  i think i just had a check if it is plunged in moment
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