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I would suggest putting a read-only domain controller in the DMZ that your proxy server can use. &nbsp;Then open up the appropriate ports to allow the domain replication to occur.
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I would suggest putting a read-only domain controller in the DMZ that your proxy server can use.  Then open up the appropriate ports to allow the domain replication to occur.

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After adding the correct rules my issue was resolved.
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After adding the correct rules my issue was resolved.

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care to share your ACL? &nbsp;I have the NAT, but not sure where the ACL goes...
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care to share your ACL?  I have the NAT, but not sure where the ACL goes...

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ASA Firewall Rules need to do the following. (Using Cisco ASDM 6.3 console)<br />
<br />
DMZ <br />
1 x ADFS Proxy server (192.168.x.x) needs to see the internal ADFS server (172.x.x.x)<br />
(I can't currently join the ADFS Proxy server to the domain)<br />
1 x Front End Web server (192.168.x.x) needs to see the internal CRM server (172.x.x.x)<br />
(I can't currently join the Front End Web server to the domain)<br />
<br />
Objective<br />
External end users with AD accounts to enter a CRM URL (crm.domain.co.uk) via browser on tablet<br />
URL points to Front End Web server in the DMZ, then redirects to the ADFS server via the ADFS proxy in the DMZ<br />
ADFS authenticates the user against the internal DC, and then the Front End Web server in the DMZ redirects to the internal CRM SQL boxes rendering CRM to the external users/s.
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ASA Firewall Rules need to do the following. (Using Cisco ASDM 6.3 console)

DMZ 
1 x ADFS Proxy server (192.168.x.x) needs to see the internal ADFS server (172.x.x.x)
(I can't currently join the ADFS Proxy server to the domain)
1 x Front End Web server (192.168.x.x) needs to see the internal CRM server (172.x.x.x)
(I can't currently join the Front End Web server to the domain)

Objective
External end users with AD accounts to enter a CRM URL (crm.domain.co.uk) via browser on tablet
URL points to Front End Web server in the DMZ, then redirects to the ADFS server via the ADFS proxy in the DMZ
ADFS authenticates the user against the internal DC, and then the Front End Web server in the DMZ redirects to the internal CRM SQL boxes rendering CRM to the external users/s.

Configuring Cisco ASA rules to allow DMZ 2 servers to see internal network

The Windows operating systems have distinct methodologies for designing and implementing networks, and have specific systems to accomplish various networking processes, such as Exchange for email, Sharepoint for shared files and programs, and IIS for delivery of web pages. Microsoft also produces server technologies for networked database use, security and virtualization.

Windows Networking

Hardware-based firewalls provide more sophisticated protection for inbound and outbound traffic than the simple Windows software firewall or the basic NAT firewalls found in routers. These devices implement techniques such as stateful packet inspection, deep packet inspection, and content filtering; and may include built-in antivirus and anti-malware protection.

Hardware Firewalls

Software firewalls, also known as host-based firewalls, provide a layer of software on one host that controls network traffic in and out of that single machine. Most operating systems now include firewall software, but many available software firewalls include central distribution, antivirus systems and disaster recovery.