Delete Files and Folders from Storage Server ('Permission or Access Denied')

A site is trying to delete a 200 GB folder (and associated files) from a network storage server, but when trying to delete many or most of the files and folders say 'Access Denied' or 'Administrator Permissions Needed' when trying to delete.  After signing on to the machine with a local and domain Admin account and attempting to take ownership of the folder and files the same message appears - and the Take Ownership process fails.  Apparently some or many of the files and folders are .NET developer-created files or copied system files.  How can one quickly and easily delete that entire folder (in one step) without having to drill down into each subfolder, reset the file and folder permissions, manually take ownership of the smaller subfolders one by one, delete, and then repeat (which seems to work but is very time consuming as there are hundreds of folders) ??  For some reason it will work at the drilled-down subfolder level but fails when attempting to do at the top folder level.  TIA ...