Windows Server 2012 has very slow Open/Save for MSOffice Apps

I have very recently installed a Windows Server 2012 Standard server into a Windows 2008 SBS Network. Local and remote access to shares good except for Office Apps which are very slow to save and open files. Can see other people have come up with various solutions relating to invalid old shares, TCPIP settings on clients and Group Update changes on Server 2012 acting as Domain Controller (this one isn't as yet).
Have not been able to pin this one down despite some alterations to TCPIP settings and checks on clients. Should I concentrate on server or clients or both?
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ajmcqueenConnect With a Mentor Author Commented:
I changed the anti-virus settings to be less stringent and the problem went away.
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