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As Lee noted, you can have multiple RAID devices with no problem ... you can even create multiple RAID arrays on most internal RAID controllers.<br />
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As long as you have enough eSATA connections, there's no problem using eSATA for both of the NAS's. &nbsp; &nbsp;As long as your eSATA ports are SATA-3, they're marginally faster than a USB v3 port ... if they're only SATA-2, the USB3 port is faster. &nbsp; &nbsp;But odds are that BOTH interfaces are faster than the sustained transfer rate of the NAS, so it won't really make any difference.
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As Lee noted, you can have multiple RAID devices with no problem ... you can even create multiple RAID arrays on most internal RAID controllers.

As long as you have enough eSATA connections, there's no problem using eSATA for both of the NAS's.    As long as your eSATA ports are SATA-3, they're marginally faster than a USB v3 port ... if they're only SATA-2, the USB3 port is faster.    But odds are that BOTH interfaces are faster than the sustained transfer rate of the NAS, so it won't really make any difference.

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THANKS, worked like a charm.
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Running Windows 7 Pro, I have a NAS (SansDigital) with a built in hardware RAID controller. I would like to add a MediaSonic Pro RAID (which also has a built in hardware RAID controller) as a backup to the SansDigital. Both have eSata connections but the MediaSonic also comes with a USB 3.0 port. Can 2 separate hardware enabled RAID (5) devices work together and be seen in Windows? If so, can I use the eSata on both boxes or should I use the USB 3.0 port on the MediaSonic?
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Running Windows 7 Pro, I have a NAS (SansDigital) with a built in hardware RAID controller. I would like to add a MediaSonic Pro RAID (which also has a built in hardware RAID controller) as a backup to the SansDigital. Both have eSata connections but the MediaSonic also comes with a USB 3.0 port. Can 2 separate hardware enabled RAID (5) devices work together and be seen in Windows? If so, can I use the eSata on both boxes or should I use the USB 3.0 port on the MediaSonic?

Running 2 separate hardware enabled RAID devices

Computer data storage, often called storage or memory, is a technology consisting of computer components and recording media used to retain digital data. In addition to local storage devices like CD and DVD readers, hard drives and flash drives, solid state drives can hold enormous amounts of data in a very small device. Cloud services and other new forms of remote storage also add to the capacity of devices and their ability to access more data without building additional data storage into a device.

Storage

RAID stands for Redundant Array of Independent Disks.

RAID is data storage technology that allows multiple drives to be used together as a single virtual drive for reasons such as fault tolerance, reliability and performance. 

There are several different levels of RAID that determine how the data is stored and the level of redundancy achieved across the drives.