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Microsoft Exchange RPC service manager encountered an unexpected error while starting. Error details: Object reference not set to an instance of an object.

After installing CU5 update Microsoft Exchange RPC Client Access does not start.
applicaton event log: Source MSExchangeRPC Event ID: 1028
Microsoft Exchange RPC service manager encountered an unexpected error while starting. Error details: Object reference not set to an instance of an object.
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Simon Butler (Sembee)
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That usually means the update didn't install properly.
Single server environment? What else is on the server that could have interfered?

Simon.
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I have tried to reset configuration of outlook anywhere.