How do I remove an Instance of a SQL Server in SQL Server 2008

Hi Experts,
The current SQL Server 2008 I am working with, has many instances of the same SQL SERVER.  For example:
we have:

These instances were created over the years, by a programmer/DBA who is no longer working at this company.
We need to free up some space in our server.  What do I have to do to remove/uninstall some of these instances?
Is it just a matter of manually deleting the files from C:\Program Files\Microsoft SQL Server\ ?

thanks in advance,
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Run the SQL Server uninstall from Add Remove Programs. You can select which instance to maintain.

See the following for visual reference.

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RayData AnalystCommented:
equally important.. before uninstalling check to see what DBs are attached and where they are stored.  Uninstalling the instance will not delete user DBs.
Good catch rlistenb.
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Microsoft SQL Server 2008

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